Jothy rosenberg biography of albert einstein
The MIT Press Spring 2018 Catalog
The MIT Press Spring 2018
DEAR FRIENDS AND READERS,
Welcome to the Spring 2018 season from the MIT Press, featuring classic writings from the likes of Amos Tversky and Norbert Wiener; a celebration of the March for Science; new works of science fiction; and a book of reflections on global dystopias edited by Junot Díaz, with contributions from Margaret Atwood, Samuel R. Delany, and other prominent voices. But this season we highlight the MIT Press Essential Knowledge Series, or EKS, which offers concise, accessible overviews of compelling topics.
Written by leading thinkers, EKS volumes provide expert syntheses on topics that have come to define the MIT Press itself, ranging from the cultural and historical to the scientific and technical.
When we first launched this ambitious series back in 2011, with John Palfrey’s Intellectual Property Strategy and James Cortada’s Information and the Modern Corporation, we couldn’t have known where it would take us and how far it would go. Seven years on, we’re celebrating thirty volumes in the series, with new works on synesthesia, data science, post-truth, and the book itself. The breadth of challenging topics, rendered accessibly, proposes a new model of literacy for citizens of our techno-centric world. EKS is quintessential MIT Press.
Enjoy! Amy Brand
front cover: Boxes containing brachiopod (Brachiopoda) shells. Museum für Naturkunde Berlin, M. Ohl photo. From The Art of Naming.
CONTENTS
Trade 1-67
Academic Trade 68-76 Professional 77-104
Paperback Reprints 105-115 Journals 116-119 MITxPress 120
The Digital MIT Press 121 Order Information 122-125 Index 126-127 Paperback Highlights 128-129 Recent Highlights 130-132 Backlist Highlights inside back cover
DISTRIBUTED BY THE MIT PRESS
Afterall Books 43 Zone Books 44 SA+P Press 45 Semiotext(e) 46-52
Strange Attractor Press 53-59 Goldsmiths Press 60-64
Boston Review 65-67
The Art of Naming
Michael Ohl translated by Elisabeth LWhat is Cloud Computing?
Introduction
Cloud computing delivers various computing services, including storage, processing, networking, databases, software, analytics, and intelligence, over the internet. It's like having a vast virtual computer that you can access anytime, anywhere, as long as you have an internet connection. Imagine having the power of an enormous data center right at your fingertips without owning any physical hardware or servers. That's cloud computing for you!
Brief History: From Floppy Disks to the Fluffy Cloud
The journey from floppy disks to the fluffy cloud is a fascinating tale of technological evolution. In the early days of computing, data was stored on physical devices like tapes and floppy disks. You could only access your data from the machine where it was saved. Remember those 1.44 MB floppy disks? Ah, those were the days!
Then came the era of hard drives and local networks, where data was more centralized. However, it was still confined within organizational boundaries.
With the advent of the internet and improved bandwidth, the concept of cloud computing began to take shape. In 2006, Amazon launched its Elastic Compute Cloud (EC2), pioneering the modern cloud era. Since then, cloud computing has soared to new heights, transforming how businesses and individuals access and utilize technology.
Importance of Cloud Computing in Digital World
In today's fast-paced digital world, cloud computing is no longer a luxury; it's a necessity. It's the backbone of modern business, powering everything from simple file sharing to complex machine learning algorithms. Here's why it's so vital:
- Scalability: Whether a startup or a multinational corporation, cloud computing grows with you.
- Accessibility: Access your data, software, and services from anywhere in the world. All you need is an internet connection.
- Cost-Efficiency: No need to invest in expensive hardware. Pay for what you u
Whirlwinds & Small Voices: Sustaining Commitment to Work with Special-Needs Children
By: Robbins, Amy McConkey,McConkey, Clarence
Price: $1.95
Publisher: Lucas Park Books : June 2010
Seller ID: 349254
ISBN-13: 9781603500098
Binding:Trade Paperback
Condition: Used - Good
Whirlwinds & Small Voices is written as a seven-day discipline to inform, inspire, and renew those who care for children with special needs - including parents and families, clergy and congregations, teachers, therapists, and members of the medical profession. This book is rich with stories of real life children, real life parents and families, and the work of therapists and technicians who know the path to the world of growth, fulfillment, and spiritual development for children. Be inspired, challenged, and informed as you read about specific, tested practices. You will not only become better...
View More...Abstract
Success of cancer vaccination is strongly hampered by immune suppression in the tumor microenvironment (TME). Interleukin (IL)-6 is particularly and highly produced by triple-negative breast cancer (TNBC) cells, and has been considered as an important contributor to immune suppression in the TME. Therefore, we hypothesized that IL-6 reduction may improve efficacy of vaccination against TNBC cancer through improved T-cell responses. To prove this hypothesis, we investigated the effect of curcumin, an inhibitor of IL-6 production, on vaccination of a highly attenuated Listeria monocytogenes (Listeria), encoding tumor-associated antigens (TAA) Mage-b in a TNBC model 4T1. Two therapeutic vaccination strategies with Listeria-Mage-b and curcumin were tested. The first immunization strategy involved all Listeria-Mage-b vaccinations and curcumin after tumor development. As curcumin has been consumed all over the world, the second immunization strategy involved curcumin before and all therapeutic vaccinations with Listeria-Mage-b after tumor development. Here, we demonstrate that curcumin significantly improves therapeutic efficacy of Listeria-Mage-b with both immunization strategies particularly against metastases in a TNBC model (4T1). The combination therapy was slightly but significantly more effective against the metastases when curcumin was administered before compared to after tumor development. With curcumin before tumor development in the combination therapy, the production of IL-6 was significantly decreased and IL-12 increased by myeloid-derived suppressor cells (MDSC), in correlation with improved CD4 and CD8 T-cell responses in blood. Our study suggests that curcumin improves the efficacy of Listeria-Mage-b vaccine against metastases in TNBC model 4T1 through reversal of tumor-induced immune suppression.
This study is focused on improving cancer vaccination by reducing immune suppression. Here we demonstrate that curcumin
- “The Cloud at Your Service”