Dj imran hassan biography of abraham

Abstract

Background

Several factors have been proposed to assess the clinical outcome of HCV infection. The correlation of HCV genotypes to possible serum markers in clinical prediction is still controversial. The main objective of this study was to determine the existence of any correlation between HCV genotypes to viral load and different clinical serum markers.

Methods

We performed a prospective cross-sectional and observational study. About serum HCV RNA positive patients were chosen from randomly selected anti-HCV positive patients. Statistical analysis was performed using the SPSS 16 software package. ROC (receiver operating characteristics) curves were used to compare diagnostic values of serum markers to predict genotypes.

Results

The most prevalent genotype was 3a (%) followed by 1a (%), 4a (%) and 3b (%) in Pakistani population. No correlation was found between viral load and serum markers for genotype 3a in a large no. of sample (n = ). While significant correlation was observed between viral load and AST in genotype 3b, ALP with viral load and ALT for genotype 1a. Patients with genotype 4a showed a significant inverse correlation with viral load and Hb level and AST with ALP. For genotype 4a, AUC (area under the curve) of ALT, ALP, AST, bilirubin, Hb level and viral load was , , , , and respectively.

Conclusions

In conclusion, there was a significant variable response of HCV genotypes with serum markers. Severity of disease is independent of serum marker level in genotype 3a, while the liver damage in genotype 4a may associate with viral cytopathic effect as well as the immune-mediated process. An index using six serum markers may correctly predict genotype 4a in patients with ≥75% accuracy.

Introduction

Hepatitis C virus (HCV) is a major cause of liver associated diseases all over the world. An estimated 3% of the world's populations (more than million people) are chronically infected with HCV, which is the main cause of liver fibrosis, cir

Professional Summary:

Dr. Adnan H. Siddiqui, is a University at Buffalo Distinguished Professor and Vice Chairman in the Department of Neurosurgery (UBNS) at the State University of New York at Buffalo’s Jacobs School of Medicine and Biomedical Sciences. He joined UBNS in December Dr. Siddiqui completed fellowship training in Interventional Neuroradiology, Cerebrovascular Surgery and Neurocritical Care from Thomas Jefferson University in Philadelphia. He completed his Neurosurgical residency at Upstate Medical University and received his PhD in Neuroscience from the University of Rochester and medical degree from Aga Khan University in Pakistan. He is a Fellow of the American Association of Neurological Surgeons, American College of Surgeons and American Heart Association. He is profoundly indebted to his mentors Nick Hopkins, Robert Rosenwasser, Charles Hodge and Shirley Joseph in shaping his career as a dual-trained cerebrovascular surgeon, clinician scientist and entrepreneur.

Dr. Siddiqui has special interest and expertise in the performance of complementary microsurgical, radiosurgical and endovascular techniques for the comprehensive management of cerebrovascular conditions. This spectrum of disease includes aneurysms and arteriovenous malformations, as well as dural, cavernous and spinal fistulae. He has special interests in endovascular management of acute ischemic stroke, as well as endovascular and microsurgical management of extracranial and intracranial vascular occlusive disease. Other clinical interests include endovascular management of intractable epistaxis, facial vascular malformations, head, neck, and brain tumor embolization and microsurgical resection of skull base tumors.

Dr. Siddiqui has over peer reviewed publications, more than 50 chapters, almost 50, citations and an H index of He is particularly proud of representing Buffalo and the US at most major cerebrovascular conferences around the worl

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One of the toughest exam in the country, the UPSC examination draws a lot of candidates each year who are full of optimism and have spent months studying hard. Most people, however, are unable to achieve victory in this exam. This article reveals a tale that will inspire people, an example of steadfast resolve and relentless devotion.

Hasan Safin, a remarkable year-old who exemplifies constant enthusiasm and tireless pursuit of goals. His adventure forges through the obstacles, ending in his triumphal rise to the title of India's youngest IPS officer, gained via his glorious victory in the UPSC Civil Services Exam.

Hasan Safin earned the distinction of becoming India's youngest IPS Officer in after earning a remarkable rank of on the UPSC Civil Services Exam. On December 23, , he began his new position as the Assistant Superintendent of Police for District Jamnagar, entering a setting that typifies his tenacious character.

Safin Hasan's Family

Safn Hasan is of the Julaha community and adheres to Islam. His father, Mustafa Hasan, worked in a diamond unit and was a part-time electrician in his hometown before that. His mother, Naseembanu, used to work as a chef in people's homes, restaurants, and banquets to pay for Safin's schooling. She is now a worker in a diamond unit. Asnain Hasan is his younger brother.

Safin Hasan's Amazing Achievements

Safin Hasan is another live example, having passed the difficult UPSC exam very early and becoming the country's youngest IPS officer. He won his first attempt at the young age of 22 with unflinching resolve, writing a historical chapter.

Safin Hasan was born and raised on July 21, , in the Gujarati hamlet of Kanodar in the Palanpur district. His life has been turbulent due to financial difficulties. His early years are evidence of the struggles that frequently beset an average lower-middle-class family, constantly making sacrifices for food, fighting for necessities, and navigating Indi